NEW INSIGHTS IN THE MANAGEMENT OF REFRACTORY NEONATAL GERD

Gastroesophageal reflux disease (GERD) is one of the most common problems in neonates. The main goals infantile GERD treatment are maintaining clinical recovery, sufficient growth, and preventing recurrence rate related problems. Acid-suppressive therapy including H2RAs PPIs basic pharmacologic for adult pediatric GERD. more effective than treatment. Neonatal remains a difficult entity to define manage, additional studies aid diagnosis management needed. refractory conservative monotherapy dilemma performing trials evaluate effect PPI or H2RA plus prokinetics these neonates necessary prevent considering invasive diagnostic procedures early surgical we performed three different survey efficacy safety combined an prokinetic neonatal monotherapy. KEYWORDS: Neonates, disease, refractory,